Niclosan (Niclosamide Bolus Tablets)

Therapeutic category

veterinary anthelmintic

Indications

It is indicated in the treatment of diphyllobothriasis caused by Diphyllobothrium latum (broad or fish tapeworm).

It is indicated in the treatment of hymenolepiasis caused by Hymenolepis nana (dwarf tapeworm) and [H. diminuta (rat tapeworm) .

It is indicated in the treatment of taeniasis caused by Taenia saginata (beef tapeworm) and [T. solium (pork tapeworm)] .

It is used in the treatment of dipylidiasis caused by Dipylidium caninum (dog and cat tapeworm).

Although niclosamide is effective in the treatment of cestode infections caused by T. solium , it causes disintegration of the proglottids with release of viable eggs into the intestinal lumen. Since this may theoretically result in cysticercosis, quinacrine, which expels T. solium intact, may be preferred by some medical experts even though it may be less convenient to administer and is more toxic. However, quinacrine commonly causes vomiting, which may predispose to egg activation in the gastrointestinal lumen.